Skip to content

Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients

Use of Diffusion Weighted Magnetic Resonance Imaging to Stage Gastric Adenocarcinoma Patients Preoperatively

Status
Completed
Phases
Early Phase 1
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01794026
Enrollment
30
Registered
2013-02-18
Start date
2013-03-31
Completion date
2013-12-31
Last updated
2017-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric Adenocarcinoma

Keywords

diffusion weighted, magnetic resonance imaging, surgery, histopathology

Brief summary

Preoperative staging for gastric adenocarcinoma is an important procedure to detect advanced disease stateS for the patients in which the surgery may be unnecessary to perform. Although there are many imaging techniques for this purpose, sensitivity and specificity of these techniques still remains to be low.Preoperative detection of peritoneal carcinomatosis and involvement of lymph nodes beyond D2 may prevent surgical procedures. Removal of the determined lymph nodes according to the type of the surgery is the accepted surgical method. However, accurate determination of malignant lymph nodes may prevent dissection of some groups of the lymph nodes. These findings may cause a new definition of gastric lymph node dissection.

Detailed description

1. proven endoscopic diagnosis of gastric adenocarcinoma 2. for staging purposes, computed tomography for all patients 3. evaluation of benign and malignant lymph nodes according to computed tomography findings and mapping of the lymph nodes 4. to state precisely resectable patients according to computed tomography and anesthetic evaluation 5. evaluation of benign and malignant lymph nodes according to diffusion weighted magnetic resonance imaging findings and mapping of the lymph nodes 6. standard gastrectomy and D2 lymph node dissection 7. mapping of the lymph nodes after taking the specimen out 8. histopathological diagnosis of the lymph nodes and mapping 9. comparison of the results taken from computed tomography, diffusion weighted magnetic resonance imaging and histopathological analysis

Interventions

for diagnostic purposes, diffusion weighted magnetic resonance imaging in all patients

Sponsors

Bezmialem Vakif University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* gastric adenocarcinoma proven by endoscopic biopsy; * application of both computed tomography and diffusion weighted magnetic resonance imaging; * standard gastrectomy and a D2 lymph node dissection; * desire to attend the study protocol

Exclusion criteria

* preoperative neoadjuvant therapy; * metastatic disease; * undesired reaction to attend the study protocol

Design outcomes

Primary

MeasureTime frameDescription
efficacy of diffusion weighted magnetic resonance imaging to detect benign and malignant lymph nodesone yearto compare the radiologic diagnosis of benign and malignant lymph nodes with histopathological diagnosis

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026