Transcranial Electrical Stimulation (TES) for the Treatment of Depression.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01792414

Enrollment

Registered

2013-02-15

Start date

2013-01-31

Completion date

2016-12-31

Last updated

2017-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depression

Brief summary

This study is a RCT of transcranial electrical stimulation in depressed patients. Mood, cognitive test performance and biomarkers will be measured during the trial.

Interventions

DEVICESham TES

Neuroconn Eldith device

DEVICEActive TES

Neuroconn Eldith device

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* DSM-IV Major Depressive Episode (as part of a Major Depressive Disorder or Bipolar Disorder), of minimum 4 weeks duration. * MADRS score ≥ 20 at study entry.

Exclusion criteria

* DSM-IV psychotic disorder; * drug or alcohol abuse or dependence (preceding 12 months); * inadequate response to ECT (current episode of depression); * anticonvulsant or benzodiazepine medication; * rapid clinical response required, e.g. high suicide risk; clinically defined neurological disorder or insult; * metal in the cranium, skull defects, or skin lesions on scalp (cuts, abrasions, rash) at proposed electrode sites; * pregnancy.

Design outcomes

Primary

Measure	Time frame
Montgomery Asberg Depression Rating Scale for Depression (MADRS)	12 weeks

Secondary

Measure	Time frame
Beck Depression Inventory II	12 weeks

Countries

Australia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 19, 2026