Hemodynamic Instability
Conditions
Keywords
Elective living donor liver transplantation
Brief summary
The aim of this study is to compare the accuracy of PVI (pleth variability index)
Detailed description
The aim of this study is to compare the accuracy of PVI (pleth variability index)with other hemodynamic variability that measured with PİCCO (SVV, PPV, CVP,CI)to predict the response of cardiac index to volume replacement in patients undergoing liver transplantation.
Interventions
In this study of 25 adult patients undergoing OLT, we prospectively record PVIwithin 5 minutes during dissection and anhepatic phase of OLT by Masimo pulse oximeter.In this study of 25 adult patients undergoing OLT, we prospectively record study data within 5 minutes during dissection and anhepatic phase of OLT. Study data included measurements of PVI,thermodilution cardiac output, Stroke volume variation (SVV) and Pulse pressure variation (PPV).
Sponsors
Inonu University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Elective living donor liver transplantation, * \>18 years patients
Exclusion criteria
Patients with: * Arrhythmia * Reduced left ventricular function (EF\<40%) * Hepatocellular carcinoma * Pulmonary hypertension * Fulminant liver failure * valvular heart disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To test the ability of PVI to detect changes in preload during orthotopic liver transplantation | During dissection and anhepatic phase (3 months) | PVI is a measure of the dynamic changes in perfusion index that occur during a complete respiratory cycle |
Countries
Turkey (Türkiye)
Outcome results
None listed