Migraine Disorders
Conditions
Keywords
Metoclopramide, Sumatriptan, migraine, headache
Brief summary
The purpose of this study is to determine which drug makes lower migraine headache
Detailed description
There are different options to manage benign headache in emergency department.The investigators compared Intravenous metoclopramide with Subcutaneous sumatriptan to relieve pain in emergency department.
Interventions
DRUGmetoclopramide, injection,20mg, one time
metoclopramide, intravenous injection,20mg, one time
DRUGSumatriptan, injection, 6 mg, one time
Sumatriptan, subcutaneous injection, 6 mg, one time
Sponsors
Isfahan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* 20-60 years old and presented with acute headache similar to previous episodes, * with or without phonophobia, * photophobia, * vomiting or nausea.
Exclusion criteria
* fever or neck stiffness, * altered mental state, * pregnancy, * recent trauma or seizure (within 24 hours), * focal neurological abnormality on physical examination, * allergy to metoclopramide, * hypertension, * cardiovascular diseases. Also if the patients had taken a triptan or ergot during the last 24 hours were excluded from the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| pain | at one hour after prescription | determining pain in Metoclopramide versus sumatriptan groups |
Countries
Iran
Outcome results
None listed