Lung Transplant
Conditions
Brief summary
Open multicentric prospective study performed on pulmonary transplanted patients to detect the values of different diagnostic markers for immuno- humoral reaction and their roles in the humoral rejection for those patients.
Interventions
BIOLOGICALBlood test for detecting the circulatory anti-HLA antibodies by ELISA and LUMINEX tests
Sponsors
Hopital Foch
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Both genders, more than 18 years of age. * Patients with or without Cystic fibrosis * Patients with no previous unilateral or bilateral pulmonary transplant or cardiopulmonary transplant * Patients with no current other disease can affect, in short term, the process or prognosis of the transplant * Patients had given his agreement to be enrolled in the study
Exclusion criteria
* Patient less than 18 year-old * Patient had previous organ transplant * Pregnant and/or lactating women * Female subject in reproductive age does not use effective contraceptive methode * Alcoholisms or neuropsychosis, conditions that affect the good comprehension of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of immune Markers of acute lung transplant rejection (Anti-HLA circulatory antibodies, neutrophils and C4d immune markers. | 12 months after pulmonary transplant |
Countries
France
Outcome results
None listed