Frequency of Residual Neuromuscular Blockade in the Pediatric Population

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01786863

Enrollment

Registered

2013-02-08

Start date

2013-02-28

Completion date

2015-12-31

Last updated

2016-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuromuscular Blockade

Brief summary

This study is designed to investigate the frequency of Residual Neuromuscular Blockade (RNMB) in the pediatric population.

Detailed description

The proposed study will be the first to investigate the incidence of residual postoperative neuromuscular blockade in the pediatric patient following the intraoperative use of NMBA's. If there is significant residual blockade present, it may be that these effects will lead to postoperative respiratory complications including hypoxemia, atelectasis, and prolonged oxygen requirement resulting in a prolonged stay in the post-anesthesia care unit.

Interventions

PROCEDURENeuromuscular blockade

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 17 Years

Healthy volunteers

Inclusion criteria

1. Age less than 18 years. 2. Surgery requiring the administration of neuromuscular blocking, agents with planned extubation in the postoperative care unit (PACU).

Exclusion criteria

1. Neuromuscular diseases which may prolong the duration of NMBA's or exaggerate the effects of residual blockade. 2. The need for postoperative mechanical ventilation. 3. Direct admission to the Pediatric ICU, NICU or CTICU.

Design outcomes

Primary

Measure	Time frame	Description
train-of-four (TOF) ratio	1 day	TOF ratio shows the residual of neuromuscular agents.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026