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Neuromuscular Consequences of Knee Arthroscopy

Neuromuscular Consequences of Knee Arthroscopy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01786772
Enrollment
39
Registered
2013-02-08
Start date
2012-11-30
Completion date
2017-12-31
Last updated
2018-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tear of Fibrocartilage of Joint

Keywords

arthroscopic partial meniscectomy, meniscus, quadriceps strength, quadriceps voluntary activation, cryotherapy, compression, vasopneumatic compression, intermittent pneumatic compression

Brief summary

To determine changes in quadriceps muscle function following the application of ice and compression to the knee.

Detailed description

Novel rehabilitation methods, that specifically target decreased muscle activation due to joint pathology prior to strength training, have elicited greater improvements in muscle function and self-reported disability compared to traditional therapies. Preliminary evidence suggests applying cryotherapy to a joint prior to exercise can increase quadriceps activation. It is unknown if applying cryotherapy and intermittent pneumatic compression can also increase quadriceps force output and voluntary activation. The purpose of this study is to determine changes in quadriceps force output and voluntary activation following the application of cryotherapy and compression. The investigators hypothesize there will be an increase in quadriceps force output and voluntary activation following the application of cryotherapy and compression.

Interventions

OTHERCryotherapy and compression

Cryotherapy and intermittent pneumatic compression will be applied to the knee joint using a recirculating compression unit and knee sleeve. This unit will recirculate water which is between 1-3° C. Circumferential intermittent pneumatic compression to the knee joint (5 to 50 mm Hg) will be applied in conjunction with cryotherapy. The duration of intervention will be 20 minutes.

OTHERCryotherapy

Cryotherapy will be applied to the knee joint using a recirculating compression unit and knee sleeve. This unit will recirculate water which is between 1-3° C. The duration of intervention will be 20 minutes.

Sponsors

Creighton University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
15 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Age 15-65 years * BMI \< 30 * Candidate for arthroscopic knee surgery to address meniscus pathology or arthroscopic knee surgery within the past 2 years.

Exclusion criteria

* Participants who are outside of age range * Ligamentous insufficiency or repair * Participants with traumatic spine or lower extremity injury within past 6 months * Participants who have had previous adverse reactions to electrical stimulation or cryotherapy (i.e. burns, hypersensitivity) * Medical conditions which would be contraindications to electrical stimulation or transcranial magnetic stimulation, including cardiac pacemaker, metal implants in the head, current pregnancy, neurological disorders, and history of seizures * Participants who are unable to give consent or are unable to understand procedures of experiment.

Design outcomes

Primary

MeasureTime frameDescription
Changes in quadriceps force output and voluntary activationBaseline and immediately following intervention (Single Study Visit)Quadriceps activation will be estimated by utilizing the burst-superimposition technique on a maximum voluntary isometric contraction (MVIC) and during a resting condition. The burst-superimposition technique provides the muscle with a percutaneous stimulus to recruit any remaining muscle fibers which have not been stimulated.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026