Pain
Conditions
Keywords
colonoscopy, pain
Brief summary
Colonoscopy may be an unpleasant procedure. Sedation and/or analgesics is therefore routinely administered in most countries. In Norway, however, routine sedation is rare, and medication is normally given on demand, that is, if necessary during the procedure. The investigators want to evaluate whether the effect of fentanyl, a synthetic opioid with fast onset of action, is better given before the procedure than during the procedure.
Interventions
DRUGRoutine medication arm
50 micrograms of fentanyl given before the procedure
DRUGFentanyl on-demand arm
Fentanyl 50 microgram is provided on-demand, that is, if the patient has pain during the procedure.
Sponsors
Sorlandet Hospital HF
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Age 18-75 * Referred for out-patient colonoscopy
Exclusion criteria
* ASA-score 3 or higher * Same day upper endoscopy * Pregnancy * Pacemaker * Patient require medication before colonoscopy * Previous resection of colon or rectum * Significant psychiatric morbidity * Oxygen saturation \< 95% without supplementary oxygen * Contra indications to fentanyl * Inability to sign inform consent * Inability to understand information about the trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain during colonoscopy | Immediately after the procedure and after 24 hours | Pain is recorded on a 4 point Likert scale and a 100 mm VAS scale. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Additional medication | During the colonoscopy | The investigators want to assess the need for additional medication during the colonoscopy in the routine fentanyl-arm compared to the fentanyl on-demand arm. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Caecum intubation time | During the procedure | Time to reach the caecum (minutes) |
| Caecum intubation rate | During the procedure | The number of complete procedures divided by the total number of procedures |
| Patient satisfaction | The day after the procedure | Patients are asked about satisfaction with information and treatment (yes/no) |
| Recovery time | Immediately after the procedure Within one hour after the procedure | Time elapsing between end of procedure until leaving the department |
| Willingness to repeat | Within one hour after the procedure | The patient is asked whether he/she would be willing to have the procedure again in the same way (yes/no). |
| Complications | During the procedure | Sedation-related complications during the procedure |
Countries
Norway
Outcome results
None listed