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Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

Effects of Low-level Laser Therapy on Global Gene Expression of Young Males Submitted to Physical Strength Training

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01784432
Enrollment
30
Registered
2013-02-05
Start date
2011-01-31
Completion date
2012-09-30
Last updated
2013-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

low-level laser therapy, muscle performance, strength training, gene expression, microarrays

Brief summary

Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, low-level laser therapy has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations on global gene expression of muscle tissue influenced by exercise associated to low-level laser therapy.

Detailed description

This study assessed muscle performance in isokinetic dynamometry and leg press device; global gene expression of muscle tissue by microarray analysis

Interventions

DEVICELow-level laser therapy and training
OTHERTraining

Sponsors

Fundação de Amparo à Pesquisa do Estado de São Paulo
CollaboratorOTHER_GOV
Centro de Pequisas de Ótica e Fotônica
CollaboratorOTHER
Faculty of Medicine of Ribeirão Preto (FMRP-USP)
CollaboratorOTHER
Fundação Hemocentro de Ribeirão Preto
CollaboratorUNKNOWN
Universidade Federal de Sao Carlos
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
MALE
Age
18 Years to 28 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy males aged between 18 and 28 years; * body mass index (BMI) equal to or less than 26 kg/m2; * moderated pattern of physical activity

Exclusion criteria

* previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study), * osseous or articular disorder in the lower limbs, * cardiovascular system disorders, * systemic disease, and * taking prescription medicines or using dietary supplements such as muscle mass builders

Design outcomes

Primary

MeasureTime frame
Global gene expression by microarray analysis12 weeks

Secondary

MeasureTime frame
Muscle performance in leg press device12 weeks
Muscle performance in isokinetic dynamometer12 weeks

Other

MeasureTime frameDescription
Immunohistochemical analysis12 weeksImmunohistochemical analysis to quantify morphology and cells of muscle tissue as satellite cells.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026