Self-consciousness in Dementia

Status

Terminated

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01782248

Enrollment

Registered

2013-02-01

Start date

2013-03-13

Completion date

2021-03-22

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer Disease, Fronto-temporal Lobar Dementia

Brief summary

The aim of this study is to characterize the deficit in critical components of personal identity (self-consciousness and social cognition) in patients with Alzheimer's disease (AD) and fronto-temporal lobar dementia (FTLD), compared to healthy elderly, combining a neuropsychology and multi-podal neuroimaging study. We posit that the alteration of some aspects of self-consciousness (autobiographical memory, nosognosia, metacognition) and social cognition (theory of mind and facial) results in personality changes in the patients, primarily due to the alteration of self-consciousness in AD and to social cognition in FTLD.

Interventions

OTHERQuestionnary and IRM

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

45 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* AD (McKhann et al, 1984 and Dubois et al, 2007) or FTLD (Neary et al, 1998 or Rascovsky et al, 2011) * MMSE \> or = 18 * Relative avaible

Exclusion criteria

* Contraindication to MRI * Major depression * Other central neurological condition

Design outcomes

Primary

Measure	Time frame
Characterize the deficit in critical components of personal identity in patients with Alzheimer's disease (AD) and fronto-temporal lobar dementia (FTLD), compared to healthy elderly, combining a neuropsychology and multi-podal neuroimaging study.	each month for 3 month

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 14, 2026