Changes in Metabolic Status in Patients With Total Thyroidectomy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01781767

Acronym

Thyroid cancer

Enrollment

Registered

2013-02-01

Start date

2013-01-31

Completion date

2014-07-31

Last updated

2013-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Cancer

Keywords

UCP2, Thyroid function, Thyroid carcinoma

Brief summary

This study objective is to evaluate the change in mitochondrial uncoupling protein 2 (UCP2) mRNA expression as function of thyroid activity (TSH, T3 and Free T4).

Detailed description

Blood will be drown before thyroidectomy, 2 weeks after the operation and 3-4 month after the operation.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients who were diagnosed with thyroid carcinoma and are going to have total thyroidectomy. * Patients with unbalanced thyroid hormones. * Aged 18-65 years at the time of screening. * Provision of written informed consent.

Exclusion criteria

* Patients with Diabetes. * Patients with any other chronic inflammatory diseases. * Steroid treatment.

Design outcomes

Primary

Measure	Time frame	Description
Changes in UCP2 mRNA concentrations.	Base line (before opporation), 2 weeks after opporation and for after opporation.	The difference between the result at two weeks and four months compare to base line.

Secondary

Measure	Time frame
Weight	Approximately 4 months
Resting energy expenditure	Approximatly 4 months

Countries

Israel

Contacts

Primary ContactNachum Vaisman, M.D.

vaisman@tasmc.health.gov.il972-3-6974807

Outcome results