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Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01781364
Enrollment
20
Registered
2013-02-01
Start date
2012-01-31
Completion date
2014-12-31
Last updated
2014-12-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Psychosis

Keywords

Brain Oscillations, Cognitive Performance

Brief summary

The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Detailed description

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Interventions

BEHAVIORALBrain Fitness Training, Posit Science SF

Computer aided cognitive training based on principles of neuroplasticity

Sponsors

University of Konstanz
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
17 Years to 37 Years
Healthy volunteers
No

Inclusion criteria

* Early Onset Psychosis

Exclusion criteria

* Chronicity * Insufficient German skills

Design outcomes

Primary

MeasureTime frame
change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activitybaseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up

Secondary

MeasureTime frame
change from baseline in GAF score at 3-months and 7-moths follow-upbaseline, 3-months follow-up, 7-months follow-up

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026