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MEVALONATE KINASE GENE MUTATIONS AND THEIR CLINICAL CORRELATIONS IN BEHÇET'S DISEASE

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01780363
Enrollment
Unknown
Registered
2013-01-31
Start date
2011-01-31
Completion date
Unknown
Last updated
2013-01-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behçet's Disease

Brief summary

Background: Genetics is suggested to play a critical role in the development of Behçet's disease (BD). Shared phenotypic features requires an approach to the differential diagnosis from periodic febrile syndromes particularly from mevalonate kinase deficiency related diseases. We planned to study for evaluating the frequency of mutations and their clinical significance in mevalonate kinase gene in Turkish patients with Behçet's disease.

Interventions

None listed

Sponsors

Cukurova University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Behçet patients

Exclusion criteria

* Diagnosis of periodic fever syndromes

Design outcomes

Primary

MeasureTime frame
Frequency of mevalonate kinase frequency in Behçet diseaseOne year

Secondary

MeasureTime frame
Mevalonate kinase gene and clinical correlations in Behçet's diseaseOne year

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026