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Oxygen Level and Safe Emergence From Anesthesia

Emergence From General Anesthesia With Laryngeal Mask Airway and Increased End-expiratory Pressure Using 30% Oxygen is as Safe as With 100% Oxygen But Reduces the Area of Post Operative Atelectasis.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01779076
Enrollment
59
Registered
2013-01-30
Start date
2013-02-28
Completion date
2013-06-11
Last updated
2018-01-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Focus of Study is Postoperative Pulmonary Atelectacis

Brief summary

Using a protective ventilation strategy during general anesthesia from pre-oxygenation to emergence and selecting patients without risk of a difficult airway or intubation, a lower fraction of inspiratory oxygen (FIO2) can be used during extubation. This might reduce the postoperative area of atelectasis without desaturations becoming more common.

Interventions

PROCEDURE30% oxygen
PROCEDURE100% oxygen

Sponsors

Region Västmanland
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
30 Years to 85 Years
Healthy volunteers
No

Inclusion criteria

* No sign of difficult airway or intubation * Day case surgery in total intravenous anesthesia with laryngeal mask airway without adding regional anesthesia of plexus brachialis or muscle relaxant. * Body mass index less than 35. * American Society of Anesthesiologists physical status (ASA) class I-III

Exclusion criteria

* Body mass index 35 or higher * Increased risk of aspiration * Obstructive sleep apnea syndrome * Procedures during surgery making a former easy airway a difficult airway * Need for opioids after extubation * Hypothermia

Design outcomes

Primary

MeasureTime frameDescription
Area of atelectasis30 minutesThe area of atelectasis is investigated by computed tomography of the lungs postoperatively

Secondary

MeasureTime frameDescription
Peripheral oxygen saturation (SpO2)3 hoursSpO2 is continuously assessed postoperatively.

Countries

Sweden

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026