Pleural Effusion
Conditions
Keywords
pleural effusion, pleural drainage, thorax impedance, respiration parameters, heart sounds analysis
Brief summary
This study investigates if data about monitoring the drainage of pleural effusion can be collected by non invasive sensors (feasibility).
Detailed description
25 patients \> 18 years old with pleura effusion will be examined with regard to the feasibility of non invasive sensor measurements corresponding to the course of thorax impedance and respiration parameters during body fluids loss before and after pleural drainage. The measured data will be compared to standard routine reference measurements (heart rate, medication, brain natriuretic peptide (BNP), heart minute volume). Additionally heart sound analysis via electronic stethoscope will be compared to standard methods. Also 25 healthy controls will undergo the same measurements to receive standard values.
Interventions
DEVICEBody Bioimpedance Sensor
Sponsors
RWTH Aachen University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
Yes
Inclusion criteria
* patients with pleural effusion undergoing pleural drainage * male and female patients aged at least 18 years
Exclusion criteria
* pregnancy or breast feeding * implanted pacemaker / Cardiac Resynchronization Therapy (CRT) / Implanted Cardioverter Defibrillator (ICD) except Medtronic Device OptiVol. * patients not being able to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of thorax impedance (Ohm) | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour. | non invasive bioimpedance measurements to determine feasibility of body fluid loss before and after pleura drainage in 25 patients \> 18 years old; also 25 healthy controls are measured to receive standard values |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of Cardiac output ( l/min) via impedance cardiography | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour | non invasive bioimpedance measurements to determine feasibility of impedance cardiography before and after pleura drainage; also 25 healthy controls are measured to receive standard values |
Other
| Measure | Time frame | Description |
|---|---|---|
| Change of respiratory parameter CO2 in %/ml exhaled air | once during hospital stay at baseline time 0 before pleura drainage and after pleura drainage at time 1 hour | respiratory parameters as CO2 in %/ml exhaled volume will be determined via capnograph |
Countries
Germany
Outcome results
None listed