Fracture
Conditions
Keywords
Fracture, Physeal injury, Diffusion MRI
Brief summary
Children who suffer fractures to the growth plates (physes) of their bones are at risk for premature growth arrest which can lead to long term complications. There is currently no technique to predict who is at risk of growth arrest following a physeal injury. The investigators aim to determine if diffusion MRI (an imaging method to analyze tissue properties) can effectively pick up differences between a healthy growth plate and an injured one. This would allow orthopaedics surgeons to predict which injuries are at a higher risk of growth arrest, so earlier interventions can be done in the orthopaedic clinic.
Detailed description
The purpose of this study is to determine if diffusion MRI can be used for tissue characterization in childhood and adolescent growth plate injuries, and to get a better understanding of the physiologic disturbance of an injured physis
Interventions
OTHERDiffusion MRI
Each subject will undergo one diffusion MRI scan to identify characteristics of their physes
Sponsors
Pediatric Orthopaedic Society of North America
University of British Columbia
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
8 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* Salter-Harris Type II, III, or IV fracture through the distal radius * Growth plates are open * Ages 8-12 * Able to consent in English
Exclusion criteria
* All fractures not sustained to distal radius * SH Type I or V fracture * Injury to contralateral limb * Previous injury to distal radius * Diseases known to alter bone healing or growth\] * Contraindications to undergoing an MRI scan
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tissue characterization of growth plate using diffusion MRI | 4-6 weeks following injury | Diffusion MRI scan of injured and contralateral (control) physis. |
Countries
Canada
Contacts
Primary ContactSameer Desai
Outcome results
None listed