Ischemic Preconditioning in Endurance Athletes

Influence of Remote Ischemic Preconditioning on Cardiac Function After Endurance Exercise

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01774461

Enrollment

Registered

2013-01-24

Start date

2013-03-31

Completion date

2013-09-30

Last updated

2014-03-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Brief summary

The aim of this study is to investigate the effect of remote ischemic preconditioning on biochemical and functional indices of cardiac function induced by a 30 km run in healthy trained long distance runners.

Interventions

OTHERRemote ischemic preconditioning

Blood pressure cuff placed on upper arm and inflated to 200mmHg for 5 minutes then deflated for 5 minutes - this cycle is repeated a total of 4 times.

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Informed consent * Healthy * Age between 18 and 65 years * Endurance-trained (two or more training sessions per week)

Exclusion criteria

* Not applicable

Design outcomes

Primary

Measure	Time frame
Serum concentrations of cardiac troponins	6 hours, 2 hourly time intervals

Secondary

Measure	Time frame
Indices of cardiac function measured by echocardiography	2 hours post-exercise

Countries

Netherlands

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026