Measurement of Retinal Venous Pressure Under Short-term Low-oxygen Environment

Measurement of Retinal Venous Pressure (Retinal Venous Pressure RVP) Under Conditions of Reduced Ambient Pressure and Oxygen Partial Pressure

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01771757

Enrollment

Registered

2013-01-18

Start date

2011-12-31

Completion date

2014-07-31

Last updated

2014-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

retinal venous pressure, reduced ambient pressure, oxygen partial pressure, short-term hypoxic changes

Brief summary

The hypothesis is that the pressure in the retinal veins increases under a short-term lack of oxygen and leads to a decreased blood circulation. On the basis of measurements in the hypobaric chamber this hypothesis should be verified.

Detailed description

Conduct a pilot study to describe and quantify the retinal venous pressure (RVP) in healthy volunteers under conditions of controlled, reduced ambient and oxygen partial pressure in the pressure chamber of the Aeromedical Institute FAI in Dübendorf, Switzerland. Obtaining evidence of the adaptation behavior of the retinal vascular system in controlled, short-term hypoxic changes.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy

Exclusion criteria

* eye diseases * systemic diseases * term medication (except contraceptives) * pregnancy * allergies to the ingredients Alcain, Tropicamide and Phenylephrine * blood pressure levels except standard (\<60 /\> 140 mmHg) * oxygen saturation (SO2) \<90%

Design outcomes

Primary

Measure	Time frame	Description
Retinal venous pressure	1 hour	Quantify the changes in the retinal venous pressure (RVP)

Countries

Switzerland

Outcome results