Evaluation of Synchrony in the Post-operative Patient

Evaluation of Synchrony in the Post-operative Patient (NAVA vs Pressure Support)

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01771341

Acronym

SYNCHRONY

Enrollment

Registered

2013-01-18

Start date

2012-02-29

Completion date

2014-12-31

Last updated

2015-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient-ventilator Asynchronism

Keywords

NAVA, post operative

Brief summary

Neurally adjusted ventilatory support improved synchronization in the medical patient. However no data are available in the postoperative patient. This way the investigators designed a prospective randomized cross over trial to evaluate this issue in the abdominal post-operative patient.

Interventions

DEVICEMAQUET SERVOi ventilator with Edi Catheter

NAVA respiratory modality

DEVICEMAQUET SERVOi ventilator

Pressure Support

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* adult \> 18 yr-old * abdominal post-operative patient * able to trigger the ventilator

Exclusion criteria

* infant * pregnancy * esophageal surgery * recent esophageal variceal bleeding

Design outcomes

Primary

Measure	Time frame	Description
Asynchrony index (AI)	8 hours	Number of asynchrony events/total respiratory rate

Secondary

Measure	Time frame	Description
PaO2/FiO2 ratio	8 hours	ratio of partial pressure arterial oxygen and fraction of inspired oxygen

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026