Neurophysiological Molecular and Developmental Analysis of the Glutamate Synapse in Autism

Autism and Glutamatergic Synapse : Research of Genetic Mutations and Identification of Clinical and Neurophysiological Markers.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01770548

Acronym

NMDA-Autism

Enrollment

497

Registered

2013-01-17

Start date

2009-01-31

Completion date

2014-06-30

Last updated

2017-01-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism

Brief summary

Neurophysiological, Molecular and Developmental Analysis of the glutamate synapse in Autism

Detailed description

Analysis about 50 genes in glutamate synapse

Interventions

GENETICanalysis of the glutamate synapse in autism

Neurophysiological, molecular and developmental analysis of the glutamate synapse in autism

GENETICDNA collection

DNA collection

OTHERAuditory evoked potentials

auditory evoked potentials

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

2 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* have a Pervasive Developmental Disorder

Exclusion criteria

* N/A

Design outcomes

Primary

Measure	Time frame
screening of about 50 genes encoding proteins of the NMDA receptor complex, chosen according to their chromosomal localisation located in hotspots depicted by genome-wide screens in large population of autistic patients	two years

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026