The Influences of Caffeine on Heart Rate Variability of Preterm Infants

The Influences of Caffeine on HRV of Preterm Infants

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01769118

Enrollment

Registered

2013-01-16

Start date

2013-01-31

Completion date

2014-01-31

Last updated

2015-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autonomic Nervous System

Keywords

Autonomic nervous system

Brief summary

Caffeine has a stimulatory effect on the ANS. This has not yet been investigated in preterm infant who get caffeine before stopping ventilation. The investigators hypothesis is that this stimulatory effect may be characterized by HRV analysis methods.

Interventions

DRUGCaffeine

Caffeine will be given according to departmental protocol

Study design

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

25 Weeks to 34 Weeks

Healthy volunteers

Inclusion criteria

* infants born before 34 weeks gestation

Exclusion criteria

* sepsis * congenital malformations

Design outcomes

Primary

Measure	Time frame	Description
Heart rate variability	1 hour	Heart rate, SD, SDNN, HF, LF, VLF, TP

Countries

Israel

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026