PINOT Follow-up Study in End-stage Kidney Disease

Patient Information About Options for Treatment (PINOT) Follow up Study: Answering Important Questions in Home Dialysis and Conservative Care.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01768624

Enrollment

721

Registered

2013-01-15

Start date

2012-10-31

Completion date

2016-09-30

Last updated

2016-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Disease

Keywords

chronic kidney disease, dialysis, pre dialysis education, transplantation, conservative care

Brief summary

The primary aims of the Patient INformation about Options for Treatment (PINOT) Follow-up Study are to determine the proportions of patients, identified in the 2009 PINOT cohort that: (i)Made the transition to home dialysis, after an initial start on center-based dialysis. (ii)Commenced dialysis, or a time-limited trial of dialysis within 3 years, after confirmed plans for conservative care. The hypotheses to be tested in the PINOT follow-up study are: 1. 50% of stage 5 chronic kidney disease patients who plan for home dialysis do not commence home dialysis within 3 years, and instead remain on centre-based haemodialysis; and, 2. less than 15% of stage 5 chronic kidney disease patients who plan for conservative care commence dialysis within 3 years.

Detailed description

The secondary aims of the follow-up study include: (i) To assess the primary reasons patients did not transition to home dialysis, in the planned home dialysis group. (ii)To compare 3 and 5 year survival rates among patients who commenced conservative care and patients who commenced renal replacement therapy. (iii) To assess the types of dialysis utilisation over a 5 year time period among the total cohort of patients. (iv)To determine how renal palliative care services were engaged for conservative care patients, and document the patient's place of death (i.e. hospital, hospice, home with community palliative care).

Interventions

PROCEDUREdialysis, kidney transplant

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Adults and children with end stage kidney disease (eGFR \<15 ml/min) who commenced renal replacement therapy or conservative care in Australia between July and September 2009

Exclusion criteria

* Patients returning to dialysis after a failed transplant, * Patients with acute renal failure

Design outcomes

Primary

Measure	Time frame
The proportion of patients who make the transition to home dialysis, after an initial start on center-based hemodialysis.	5 years

Secondary

Measure	Time frame
The proportion of patients who commence dialysis, or have a time-limited trial of dialysis within 3 and 5 years, after a confirmed plan for conservative care.	5 years

Countries

Australia, United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026