Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis

Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative Endophthalmitis.

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01768078

Acronym

Endophtalmitis

Enrollment

112

Registered

2013-01-15

Start date

2008-09-30

Completion date

2014-10-31

Last updated

2018-12-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Endophthalmitis

Brief summary

One useful effect of early intravitreal corticotherapy is to diminish inflammatory complications after endophthalmitis, which may cause, at least in part, serious complications (retinal detachment, macular edema) which are, more than the infection, causes of the complications seen after acute endophthalmitis.

Interventions

PROCEDUREIntravitreal injection of Betamethasone + antibiotics

PROCEDUREIntravitreal injection of antibiotics

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* All patients male or female with no age limit * Hospitalized for the diagnosis and treatment of acute endophthalmitis following cataract surgery * Who had given their consent after being informed about intravitreal corticotherapy

Exclusion criteria

* Patients who refused or were unable to give their consent * Prior intravitreal corticotherapy

Design outcomes

Primary

Measure	Time frame
Measure the evolution of visual acuity	up to12 months

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026