Methemoglobinemia After Liposuction - Diagnostic by Pulse Oximetry and Blood Gas Analysis.

Methemoglobinemia After Liposuction Under Tumescent Local Anesthesia - Timecourse and Diagnostics by Pulse Oximetry and Blood Gas Analysis.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01766999

Enrollment

133

Registered

2013-01-11

Start date

2008-08-31

Completion date

2010-12-31

Last updated

2020-11-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Methemoglobinemia

Keywords

pulse oximetry, tumescent anesthesia

Brief summary

Tumescent local anesthesia is a procedure which is frequently performed for plastic cosmetic surgical procedures such as liposuction. The subcutaneous adipose tissue is infiltrated with large volumes of a solution which also contain local anesthetics. However local anesthetics, can also lead to a marked production of methemoglobin. New generation pulse oximeters are able to measure SpMetHb non-invasivly. The aim of this study is: 1. to investigate multi-wavelength pulse oximetry as a monitoring method for patients at increased risk for methemoglobinemia. 2. to illustrate MetHb concentrations over a course of 24 hours after a liposuction employing tumescent anesthesia has been carried out.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* planned liposuction in tumescent local anesthesia

Exclusion criteria

* hematologic disorders

Design outcomes

Primary

Measure	Time frame
Correlation between hemoximetric and pulseoximetric measured methemoglobin	24 hours

Secondary

Measure	Time frame
Time course of MetHb concentration following liposuction employing tumescent anesthesia.	24 hours

Outcome results