Decoding Chronic Pain With fMRI

Observational Study to Determine Abnormalities in Resting State fMRI in Chronic Back Pain.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01766973

Enrollment

Registered

2013-01-11

Start date

2013-04-06

Completion date

2018-06-06

Last updated

2018-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Back Pain

Brief summary

Recent evidence suggests that chronic pain is associated with abnormal connectivity between brain regions associated with the processing of pain. We aim to test the diagnostic power of resting state functional magnetic resonance imaging (MRI) to diagnose patients with chronic back pain. Using new methods of image acquisition and analysis we aim to develop a computational method to correctly classify patients and matched control subjects.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* age 18-60 * pain \> 6months * right-handed * non-smoking * mechanical back pain

Exclusion criteria

* significant neurological or psychiatric disease * major systemic illness * MRI

Design outcomes

Primary

Measure	Time frame	Description
Functional brain connectivity	6 months	Assessed by fMRI

Countries

United Kingdom

Outcome results