Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort)

Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort): Seek Correlations Between Signs of Neurological and Vascular Degeneration and Signs of Ocular Aging

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01766596

Acronym

Enrollment

1153

Registered

2013-01-11

Start date

2009-10-31

Completion date

2019-11-04

Last updated

2024-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AMD, Glaucoma

Keywords

Ophthalmology, Age-related ocular pathologies

Brief summary

The aim of the study proposed in Dijon is above all to focus on the possible relationship between age-related ocular pathologies (AMD and glaucoma) and et les degenerative neurological and cardiac pathologies. The principal objective is to seek in subjects who have undergone cerebral MRI and echocardiography, associations between the thickness of postganglionic fibers measured by Optical Coherence Tomography at the 7th year (n=1500) and signs of cerebral impairment (psycho-cognitive tests, circulation time, MRI signs). This association will be studied after taking into account the principal environmental (particularly dietary) and genetic risk factors.

Interventions

PROCEDUREOptical Coherence Tomography

Study design

Allocation

Intervention model

SINGLE_GROUP

Masking

NONE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Persons who have given their written consent * Persons who are taking part in the Dijon 3C study

Exclusion criteria

* Persons who are not registered with social security agency * Persons who are unable to sit upright during a consultation

Design outcomes

Primary

Measure	Time frame	Description
Measure the mean thickness of postganglionic fibers	T=7 years of the 3C cohort	Measure the thickness of postganglionic fibers by Optical Coherence Tomography in the 4 quadrants of the peripapillary sclera.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026