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Delivery Method and Risk for Urogenital Prolapse 15-20 Years Later

Delivery Method and Risk for Urogenital Prolapse 15-20 Years Later

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT01766193
Acronym
uropro
Enrollment
1641
Registered
2013-01-11
Start date
2012-08-31
Completion date
2014-02-28
Last updated
2017-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fecal Incontinence, Urinary Incontinence, Uterine Prolapse

Keywords

Delivery, obstetric, Obstetric Surgical Procedures, Vacuum Extraction, Obstetrical, Cesarean Section, Obstetrical Forceps, Epidemiology, Norway

Brief summary

The lifetime risk for a woman to undergo surgery for either vaginal prolapse or urinary incontinence is high. Previous studies have shown that pregnancy and childbirth are risk factors for developing prolapse. There is a lack of studies that follow women several years after delivery aiming to find whether symptoms of prolapse are linked to delivery method, ie vacuum, forceps, normal vaginal delivery and cesarean section. The investigators plan this study is to get more knowledge about pathology of prolapse and incontinence, to enable development of preventive strategies for these conditions. Aim of the study is to determine whether the prevalence of symptoms and performed surgery for urogenital prolapse differs among women delivered by vacuum, forceps, normal vaginal delivery and cesarean section 15-20 years after their first delivery. The investigators identify women that delivered their first child at St. Olavs Hospital, Trondheim, Norway between 1990-1997. Questionnaires will be sent to 2500 women (PFIQ-7, PFDI-20, PISQ-12), 600 of whom will get a clinical examination, where pelvic floor musculature is examined by palpation and 4D ultrasound, and a POP-Q quantification of prolapse performed.

Interventions

PROCEDUREvaginal delivery
PROCEDUREforceps extraction

vaginal delivery by forceps extraction

PROCEDUREvacuum extraction

vaginal delivery by vacuum extraction

PROCEDUREcesarean section

Sponsors

St. Olavs Hospital
CollaboratorOTHER
Norwegian University of Science and Technology
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
40 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* first delivery in time period 1990-1997 * vaginal birth, spontaneous, forceps or vacuum extraction, or cesarean section * residency in Klæbu, Malvik, Melhus, Midtre Gauldal, Rissa, Selbu, Trondheim, Tydal, Åfjord at the time of first delivery

Exclusion criteria

* stillbirth * breech birth * congenital Abnormalities * residency outside the 9 selected communities * forceps delivery following previous vacuum extraction delivery or spontaneous vaginal birth * vacuum extraction delivery following previous forceps delivery or spontaneous vaginal birth * Vaginal birth following previous cesarean section

Design outcomes

Primary

MeasureTime frame
symptoms of urogenital prolapse15-20 years after first delivery
surgery for urogenital prolapse15-20 years after first delivery

Secondary

MeasureTime frame
damage to pelvic floor musculature15-20 years after first delivery
urinary incontinence15-20 years after first delivery
anal incontinence15-20 years after first delivery

Countries

Norway

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026