Ageing
Conditions
Keywords
Exercise, Elderly, Blood volume, Hemoglobin
Brief summary
Hypothesis: Exercise will reduce morbidity and mortality rates in an elderly population. The extent of reduction will be intensity dependent. As part of the Generation 100 study, this sub-study project will investigate the effect of exercise on blood volume, cardiopulmonary health and heart function in healthy aging. Objective is to determine the acute effect of one endurance training session on blood volume in healthy elderly. The working hypothesis is that one interval training session increases total blood volume by 10% in healthy elderly, and that there will be no change after moderate continuous training.
Interventions
BEHAVIORALhigh intensity interval training
BEHAVIORALmoderate intensity training
Sponsors
Norwegian University of Science and Technology
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
70 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* ability to walk at least 1km, * born in 1938,1939,1940,1941 or 1942 * Sufficiently good health to be able to take part in the study, as determined by the researchers
Exclusion criteria
* Illness or disability that precludes exercise or hinders completion of the study * Uncontrolled hypertension * Symptomatic valve disease, hyper tropic cardio-myopathy or unstable angina * Active cancer * Test results indicating that study participation is unsafe * Inclusion in other studies conflicting with participation in this one
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| total blood volume | 24 hours | carbon monoxide-rebreathing spirometry (Bayreuth, Germany) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| hemoglobin volume | 24 hours | carbon monoxide-rebreathing spirometry (Bayreuth, Germany) |
Countries
Norway
Outcome results
None listed