Anxiety Disorders, Substance Use Disorders
Conditions
Keywords
anxiety disorders, substance use disorders, treatment effectiveness, cognitive behavioral therapy
Brief summary
Anxiety disorders are highly prevalent among those with substance use disorders, but the majority of addictions treatment centers provide little to no evidence-based treatment for anxiety disorders. Furthermore, tension reduction models suggest that treating anxiety should also improve substance use outcomes. This study is aimed at improving symptoms for people who have substance use and anxiety problems. The study is comparing regular Intensive Outpatient treatment for addiction to Intensive Outpatient treatment for addiction plus treatment for anxiety disorders. Clinicians at a community addictions clinic will participate by receiving training in delivering cognitive behavioral therapy for anxiety disorders and will deliver the treatment to the patient participants. They will also complete some questionnaires. Patient participants will be asked to complete a baseline assessment. Those who are eligible will be randomly assigned to one of the two treatment groups. Those who are assigned to addiction treatment as usual will continue their regular care at the Matrix Institute. Participants who are assigned to also receive the anxiety treatment will be asked to participate in 6, 90-min treatment sessions and an orientation session. All participants will be asked to complete post-treatment and follow-up assessments. The assessments should take approximately 1 hour, and the follow-up assessment will be completed 6 months after treatment is over. It is hypothesized that those who get the additional anxiety disorder treatment will show greater improvement in anxiety and substance use outcomes than those who get Intensive Outpatient Program without the anxiety disorder treatment.
Interventions
BEHAVIORALCALM-SUD
6-session group for anxiety disorders. Cognitive behavioral therapy including self-monitoring, relaxation, cognitive restructuring, exposure therapy, and relapse prevention. In addition, participants in this arm are also enrolled in an Intensive Outpatient Program for their substance use disorder. The program is run by an outpatient addictions facility and includes up to 16 weeks of groups that meet 3 to 4 times per week in addition to up to 10 individual sessions of therapy. The group model includes motivational interviewing, cognitive behavioral therapy, contingency management, and relapse prevention skills.
BEHAVIORALTreatment as usual
The program is run by an outpatient addictions facility and includes up to 16 weeks of groups that meet 3 to 4 times per week in addition to up to 10 individual sessions of therapy. The group model includes motivational interviewing, cognitive behavioral therapy, contingency management, and relapse prevention skills.
Sponsors
University of California, Los Angeles
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* 18-60 years old * speak English * meet diagnostic criteria for at least one anxiety disorder * score at least an 8 on the OASIS (see Assessments), indicating at least moderate but clinically significant anxiety symptoms * be enrolled in the Intensive Outpatient Program (IOP) at the Matrix Institute (community partner) * meet diagnostic criteria for substance abuse or dependence
Exclusion criteria
* have unstable medical conditions * marked cognitive impairment * active suicidal intent or plan * active psychosis * unstable Bipolar I disorder.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Brief Symptom Inventory | baseline, 6 weeks, 6 months | Change over time is being assessed. |
| Timeline Follow Back | baseline, 6 week, 6 month | Change over time is being assessed |
| Overall Anxiety Severity and Impairment Scale | baseline, 6 week, 6 month | Change over time is being assessed. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Panic Disorder Severity Scale | baseline, 6 week, 6 month | Change over time is being assessed. |
| Social Phobia Inventory | baseline, 6 week, 6 month | Change over time is being assessed. |
| urine toxicology screen | baseline, 6 week, 6 month | Change over time is being assessed. |
| Posttraumatic Stress Disorder Checklist | baseline, 6 week, 6 month | Change over time is being assessed. |
| Penn State Worry Questionnaire | baseline, 6 week, 6 month | Change over time is being assessed. |
| Patient Health Questionnaire-8 | baseline, 6 week, 6 month | brief depression measure; Change over time is being assessed. |
| Anxiety Sensitivity Index | baseline, 6 week, 6 month | Change over time is being assessed. |
Countries
United States
Outcome results
None listed