HIV
Conditions
Keywords
HIV, serodiscordant couples HIV sero-conversion, anti-retroviral therapy, intervention
Brief summary
The purpose of this study is to evaluate the effectiveness of reducing HIV transmission among sero-discordant couples by applying comprehensive intervention components.
Detailed description
A cluster-randomized controlled trial was carried out in forty counties from 16 cities. The strategy of Social Marketing was applied to influence sero-discordant couples' behavioral changes including safer sexual intercourses, regular HIV testing for the negative partners, antiretroviral therapy initiation.
Interventions
BEHAVIORALcomprehensive intervention components
ART promotion, Couple testing and consulting promotion, and Condom use promotion
Sponsors
National Center for AIDS/STD Control and Prevention, China CDC
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 59 Years
Healthy volunteers
No
Inclusion criteria
* Couples are required to have a stable relationship and live together in the last 3 months; * Older than 18 years and younger than 60 years; without regard to CD4 count; * Open cohort(any newly diagnosed serodiscordant couples who are eligible for treatment will be included during the study period).
Exclusion criteria
* Couples are not have a stable relationship or do not live together in the last 3 months; * Younger than 18 years old.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HIV seroconversion rate of HIV negatives among HIV serodiscordant couples | up to 2 years |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of HIV positives receiving ART among HIV serodiscordant couples | up to 2 years |
| The incidence rate of AIDS-related diseases of HIV positives among serodiscordant couples | up to 2 years |
Countries
China
Outcome results
None listed