Three Different Approaches for Ultrasound Guided Femoral Nerve Block for Patients Undergoing Total Knee Arthroplasty

A Randomized, Single Blind Study of the Efficacy and Safety of Three Different Approaches for Ultrasound Guided Femoral Nerve Block for Patients Undergoing Total Knee Arthroplasty

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01763814

Enrollment

108

Registered

2013-01-09

Start date

2011-12-31

Completion date

2019-04-30

Last updated

2019-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Arthroplasty

Brief summary

Patients scheduled to have a surgery for Total Knee Arthroplasty will be assigned to one of three groups, each group will use a different approach using the ultrasound to guide the femoral nerve block as part of their treatment for controlling pain post-operatively.

Detailed description

This will be a prospective, single-blinded, randomized study. The patients will be randomly assigned to one of three groups: Group I - single shot femoral nerve block Group II - continuous femoral nerve block - non stimulating catheter Group III - continuous femoral nerve block - stimulating catheter

Interventions

PROCEDUREFemoral nerve block

A visible or palpable cephalad movement of the patella will confirm needle placement.

PROCEDUREFemoral nerve block non stimulating catheter

A visible or palpable cephalad movement of the patella will confirm needle placement. The catheter will be placed with the nerve stimulator powered off.

PROCEDUREFemoral nerve block stimulating catheter

A visible or palpable cephalad movement of the patella will confirm needle placement. The catheter will be placed with the nerve stimulator powered on.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 90 Years

Healthy volunteers

Inclusion criteria

* 18- 90 years old * Scheduled for total knee arthroplasty

Exclusion criteria

* Redo surgery on the same knee * BMI ≥45 * Radicular pain in the same leg * Allergy to local anesthetics * Opioid habituation * Pregnancy * Contraindication to regional block * Inability to communicate with hospital staff or investigators. * Neuropathy of any etiology in the surgical extremity.

Design outcomes

Primary

Measure	Time frame	Description
Change in the Numeric Rating Pain Score	Postoperative	At the conclusion of the surgery time 0, at 15, 30, and 45 minutes, at 1, 12, 24, 48 hours, and day 3, 7, 14, and 30 after the surgery.

Secondary

Measure	Time frame	Description
Change in the ability to move the knee	Postoperative	At the conclusion of the surgery time 0, at 15, 30, and 45 minutes, at 1, 12, 24, 48 hours, and day 3, 7, 14, and 30 after the surgery.
Change in Supplemental pain medications	Postoperative	At the conclusion of the surgery time 0, at 15, 30, and 45 minutes, at 1, 12, 24, 48 hours, and day 3, 7, 14, and 30 after the surgery.

Other

Measure	Time frame	Description
Change in the overall satisfaction	Postoperative	At the conclusion of the surgery time 0, at 15, 30, and 45 minutes, at 1, 12, 24, 48 hours, and day 3, 7, 14, and 30 after the surgery.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026