Colorectal Cancer
Conditions
Keywords
Colon cancer, rectal cancer, liver metastasis, survival, biomarker, molecular profile
Brief summary
* A prospective, observational study on clinical outcomes of surgical management of primary and metastatic colorectal cancer * Prospective collection of tissues to explore potential biomarkers in blood and/or primary or secondary cancers and/or normal colon
Detailed description
Prospective project in collecting and assessing clinical outcomes data related to molecular profiling of tumors based on cancer primary or metastatic tissue or tissue from peripheral blood samples. As a future part of the project will be collected patient reported outcomes (PROs) for assessing clinical outcomes in relation to clinical pathways, patient reported results, as well as tumor profiling by molecular methods.
Interventions
PROCEDUREopen and laparoscopic surgery
Curative surgery for either primary (colorectal cancer, crc) or metastatic CRC (liver surgery)
Sponsors
Helse Stavanger HF
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of colorectal cancer, primary or metastatic (liver), with a treatment intention of planned curative surgery * Informed consent to participate * Age ≥18
Exclusion criteria
* failure to provide written informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cancer-specific survival | 5-years | Time from surgery to death of cancer |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence-free survival | 3 and 5 years | Time from surgery to recurrence of cancer |
Countries
Norway
Contacts
CONTACTRamesh L. Kajavi, RN
CONTACTMarina Alexeeva, PhD
PRINCIPAL_INVESTIGATORKjetil Søreide, MD, PhD, FRCS, FACS
Helse Stavanger HF
Outcome results
None listed