Prostate Cancer
Conditions
Keywords
Prostate cancer, Androgen deprivation therapy, Exercise, Xbox
Brief summary
The purpose of this study is to investigate the effect of 12 weeks systematically training using the Xbox Kinect system. Outcome measures are made on physical function, quality of life, fatigue and metabolic parameters.
Detailed description
Patients will be recruited from the outpatient clinic at the urological department, Regionshospitalet Holstebro. Patients who have been discharged from the outpatient clinic due to biochemical stabile cancer prostate disease will receive a letter with information about the study. A research assistant will be responsible for randomization and test procedures. A physiotherapist will be responsible for instruction of the participants to the training and the Xbox system. A student will be responsible for installation and collection of the Xbox system in the participants home.
Interventions
BEHAVIORALHome based training using the Xbox Kinect system
Home based training 3 times a week for 12 weeks using the Xbox Kinect system
Sponsors
Hospitalsenheden Vest
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
40 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Prostate cancer requiring androgen deprivation therapy * Androgen deprivation therapy for at least 3 month prior to inclusion * Cognitive well-functioning in order to be able to answer questionnaires and train according to instructions * Signed informed consent
Exclusion criteria
* Prostate cancer with metastasis to other regions than bones * Strength- or cardiovascular training 2 times or more per week prior to inclusion * Haemoglobin percentage less than 6,1 mmol/l * Any mental or physical condition that makes the patient unfit for participation * Men in risk of getting an osteoporotic fracture due to long-term treatment with steroids or earlier fractures due to minimal trauma * Participation in other studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The effect of 12 weeks systematically training with the Xbox Kinect system on physical function | Change from baseline to week 12 | 6 min walk test |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The effect of 12 weeks systematically training with the Xbox Kinect system on physical function | Change from baseline to week 12 | Leg extensor power |
| The effect of 12 weeks systematically training with the Xbox Kinect system on fatigue | Change from baseline to week 12 | Fatigue measured using the Functional Assessment of Canter Therapy-Fatigue questionnaire |
| The effect of 12 weeks systematically training with the Xbox Kinect system on quality of life | Change from baseline to week 12 | Quality of life measured using the Functional Assessment of Canter Therapy-Prostate questionnaire |
| The effect of 12 weeks systematically training with the Xbox Kinect system on metabolic parameters | Change from baseline to week 12 | Waist circumference (cm) |
| The effect of 12 weeks systematically training with the Xbox Kinect on body composition | Change from baseline to week 12 | Method: BIoelectrical impedance analysis Bioelectrical impedance |
| The effect of 12 weeks systematically training with the Xbox Kinect system on insulin | Change from baseline to week 12 and week 24 | Insulin (pmol/L) |
| The effect of 12 weeks systematically training with the Xbox Kinect system on insulin resistance | Change from baseline to week 12 and week 24 | Homeostasis model assessment for insulin resistance (HOMA-IR) |
| The effect of 12 weeks systematically training with the Xbox Kinect system on Insulin Growth Factor-I (IGF-I), bioactive IGF, and IGF-II | Change from baseline to week 12 and week 24 | IGF-I, bioactive IGF and IGF-II (µg/L) |
| The effect of 12 weeks systematically training with the Xbox Kinect system on Insulin Growth Factor Binding Protein 1-3 (IGFBP 1-3) | Change from baseline to week 12 and week 24 | IGFBP 1-3 (µg/L) |
| The effect of 12 weeks systematically training with the Xbox Kinect system on the prevalence of the metabolic syndrome | Change from baseline to week 12 | The five components of the metabolic syndrome: blood glucose, triglyceride, HDL-cholesterol, waist circumference, blood pressure |
Countries
Denmark
Outcome results
None listed