Hypospadias
Conditions
Keywords
hypospadias, bladder outlet obstruction, ultrasonography
Brief summary
Even successfully managed hypospadias without any complication, voiding problem could be developed due to the increased urethral resistance. The investigators are trying to analyze the effect of hypospadias operation on voiding function by checking the detrusor thickness and urinary nerve growth factor.
Interventions
None listed
Sponsors
Yonsei University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
No minimum to 5 Years
Healthy volunteers
Yes
Inclusion criteria
\<Group 1\> 1. 6Mo-2Yr old penile hypospadias patients before operation \<Group 2\> 2. 6Mo-2Yr old male patients without hypospadias \<Group 3\> 3. penile hypospadias patients under the age of 5 Yr who got tubularized incised plate operation at out institution at the age between 6Mo and 2Yr old and more than 1 Yr have passed \<Group 4\> 4. 2Yr-5Yr old male patients without hypospadias1. 0-3 year old children without any abnormality of urinary tract
Exclusion criteria
\<Group 1, 2, 4\> 1\. patients with history of urethral operation, febrile urinary tract infection, neurogenic abnormality om operation \<Group 3\> 1. patients with history of urethral operation other than hypospadias repair, febrile urinary tract infection, neurogenic abnormality 2. patients with development urethra-cutaneous fistula
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detrusor thickness | immediate analysis of detrusor thickness at the enrollment time of this study |
Secondary
| Measure | Time frame |
|---|---|
| urinary nerve growth factor level | immediate analysis of urinary nerve growth factor level at the enrollment time of this study |
Countries
South Korea
Outcome results
None listed