Symptomatic Severe Aortic Valve Stenosis in Older Patients
Conditions
Keywords
Aortic valve stenosis, Quality of life, Burden co morbidities, Transcatheter aortic valve implantation, Geriatric assessment
Brief summary
The aim of the study is to determine whether the burden of comorbidities measured by CIRS-G (Cumulative Illness Rate Scale) is associated with a non-amelioration of the health related quality of life measured by questionnaire called "SF-36", six months after a transcatheter aortic valve replacement in older patients. During the comprehensive geriatric assessment realized before the valve implantation, the following data are recorded and their impact of the health related quality of life will also be analysed: comorbidity, age, depression, functional status, the cognitive impairment and malnutrition.
Interventions
OTHERanswering to questionnaires of quality of live
Sponsors
Nantes University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
75 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged 75 years and older * Patients referred for a transcatheter aortic valve implantation * Patients who have a comprehensive geriatric assessment realized during the three months before the valve implantation * Patients who provide informed written consent
Exclusion criteria
* Patients who refuse the study * Patients with a legal guardian
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference of the physical component summary score of the health survey scale called "SF36", between inclusion and one month after the valve implantation. | 1 month |
Secondary
| Measure | Time frame |
|---|---|
| Difference of the physical component summary score of the health survey scale called "SF36", between inclusion and three months after the valve implantation. | three months |
| Difference of the physical component summary score of the health survey scale called "SF36", between inclusion and six months after the valve implantation. | six months |
| Difference of the score of the Instrumental Activities of Daily Living scale called "IADL", between inclusion and one month after the valve implantation. | one month |
| Difference of the score of the Instrumental Activities of Daily Living scale called "IADL", between inclusion and three months after the valve implantation. | three months |
| Difference of the score of the Instrumental Activities of Daily Living scale called "IADL", between inclusion and six months after the valve implantation. | six months |
| Difference of the score of the Geriatric Depression Scale (GDS), between inclusion and one month after the valve implantation. | one month |
| Difference of the score of the Geriatric Depression Scale called "GDS", between inclusion and three months after the valve implantation | three months |
| Difference of the score of the Geriatric Depression Scale scale called "GDS", between inclusion and six months after the valve implantation | six months |
| Complications during the six months of follow up with all causes of mortality | 6 months |
Countries
France
Outcome results
None listed