Varicocele; Male Infertile;Varicocelectomy
Conditions
Keywords
varicocele; male infertile;varicocelectomy
Brief summary
The purpose of this study is to determine whether high ligation of spermatic vein by open operation and microsurgery for patients with are effective in the treatment of varicocele and to determine which surgical option is better.
Interventions
PROCEDUREopen operation
high ligation of spermatic vein by open operation
PROCEDUREmicrosurgery
high ligation of spermatic vein by microsurgery
Sponsors
First Affiliated Hospital, Sun Yat-Sen University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
10 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* 1.infertile patient suffering from varicocele 2.severe varicocele patient with obvious symptoms 3.adolescents suffering from severe varicocele with or without orchiatrophy
Exclusion criteria
* 1.varicocele patient with abdominal infection 2.varicocele patient who has massive adhesion of pelvic tissue due to pelvic surgery history 3.mild varicocele 4.varicocele patient has no obvious symptoms if has have born children, suffer from idiopathic azoospermia，or their partner can't bear children
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the quality of semen and the level of sexual hormone | before and three and six months after surgery | The semen analyses and were sexual hormones determinations conducted before and three and six months after surgery.Then the quality of semen and the level of sexual hormone before and after surgery were compared. |
| complications | one, three and six months postoperation | the complications such as recurrence, hydrocele,orchiatrophy and wound infection were assessed one, three and six months postoperation. Color doppler ultrasonography and physical examination are the main methods to assess the complications |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| If there was pain, visual analogue scale,Numerical rating scale and verbal rating scale would be used to evaluate pain intensity. pain intensity | before and one,three and six months after surgery | If there was pain, visual analogue scale,Numerical rating scale and verbal rating scale would be used to evaluate pain intensity. |
Other
| Measure | Time frame | Description |
|---|---|---|
| general information | before surgery | Before surgery, all patients were diagnosed by physical examination and testified by color Doppler ultrasound. And we documented the patients' age, left unilateral or bilateral and the grade of varicocele |
Countries
China
Outcome results
None listed