Coronary Artery Disease
Conditions
Keywords
CT coronary, Coronary arterial disease, ivabradine, metoprolol
Brief summary
Ivabradine may be better than Metoprolol for controlling heart rate before Coronary CTA.
Interventions
DRUGIvabradine and Metoprolol
Sponsors
Phramongkutklao College of Medicine and Hospital
Col. Suthee Panichkul
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Caregiver)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* elective patient on scheduled for 640 slices CT coronary at Phramonkutklao hospital * Resting heart rate \> 70 BPM * age \> 18 years and informed consent
Exclusion criteria
* Heart rate \> 100 BPM * BP \<100/60 mmHg * recent congestive heart failure in 1 mo. * SA node, AV node disease and AF * on permanent pacemaker * CrCL \< 15ml/min. , AST or ALT \> 3x UNL * on HR reducing drug such as diltiazem, verapamil, digitalis * contraindication for ivabradine or metoprolol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate of patient before CT coronary | 1 January 2013 to 31 december 2013 |
Secondary
| Measure | Time frame |
|---|---|
| safety and side effect of Metoprolol and Ivabradine | 1 january 2013 to 31 december 2013 |
Other
| Measure | Time frame |
|---|---|
| Image quality | 1 january 2013 to 31 december 2013 |
Countries
Thailand
Contacts
Primary ContactPurich Surunchupakorn, M.D.
Outcome results
None listed