Healthy Volunteers
Conditions
Brief summary
The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.
Interventions
DIETARY_SUPPLEMENTSupplement
Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.
Sponsors
Barnes-Jewish Hospital
Washington University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
40 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* age 40-60 yr * body mass index of 21 - 30 kg/m2 * sedentary to moderately active * eating a typical US diet
Exclusion criteria
* history of any chronic disease other than mild osteoarthritis * use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives * use of nutritional supplements * smoking * alcohol intake greater than two drinks per day for women and three drinks per day for men
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid-femoral pulse wave velocity | Baseline and 6 months |
Countries
United States
Outcome results
None listed