Chronic Migraine, Medication Overuse Headache
Conditions
Keywords
Chronic Migraine, Medication Overuse Headache, Refractory, transcranial direct current stimulation
Brief summary
The purpose of the study is to evaluate the efficacy of the transcranial direct current stimulation of the primary motor cortex (M1) in patients affected by refractory chronic migraine (coded as 1.5.1 in the international headache classification 2nd edition, 2004) and medication-overuse headache (coded as 8.1) with migraine as primary headache.
Interventions
DEVICESham transcranial direct current stimulation
Sponsors
Dr Armando Perrotta, MD, PhD
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Chronic MIgraine or Medication Overuse Headache according to the diagnostic criteria set out in the 2nd edition of the International Classification of Headache Disorders refractory to treatment according to the Refractory Headache Special Interest Section of the American Headache Society (Schulman et al., 2008)
Exclusion criteria
* Other primary or secondary headaches. * Any serious systemic or neurological disease or psychiatric disorder. * Pregnancy or breastfeeding * Previous or current use of other or similar devices for pain control * Heart conduction and rhythm disorders * Cranial surgery * Other pain conditions, accordingly with current guidelines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in headache days per months | at 30, 60 and 90 days after the treatment |
| Change in drugs intake per months | at 30, 60 and 90 days after treatment |
Secondary
| Measure | Time frame |
|---|---|
| Change in mean pain intensity score per months | at 30, 60 and 90 days after treatment |
Outcome results
None listed