Malnutrition
Conditions
Keywords
vitamin A, complementary foods, malnutrition, children
Brief summary
This study tried to prove that children given food supplements containing vitamin A would have better liver vitamin A stores than children given food supplements without vitamin A over a 5 month period.
Detailed description
The study wanted to assess the effect of fortification of home based complementary foods on vitamin A status in Ghanaian children who receive food supplements known as Sprinkles. The study assessed the vitamin A status and body pool size in children using a test known as the modified relative dose response test (MRDR) tests and stable 13C2 retinol as a tracer, among those who receive Sprinkles with or without vitamin A through home fortification of complementary foods.
Interventions
DIETARY_SUPPLEMENTVitamin A supplements
Sprinkles with Vitamin A
DIETARY_SUPPLEMENTSprinkles without Vitamin A
Active comparator
Sponsors
University of Wisconsin, Madison
Kintampo Health Research Centre, Ghana
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
6 Months to 12 Months
Healthy volunteers
Yes
Inclusion criteria
Informed consent of mother of eligible children aged 6-12 months. Willingness to remain in the study area for entire duration of the study. Willingness to agree to feed the child with supplied micronutrient supplements for duration of study. The child should have started taking complementary foods in addition to breast milk. Child's haemoglobin level of at least 70 g/L.
Exclusion criteria
Child's haemoglobin level less than 70 g/L. Unable to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vitamin A status after 5 months supplementation | 5 months |
Secondary
| Measure | Time frame |
|---|---|
| acceptability of home based fortified vitamin A supplements | 5 months |
Countries
Ghana
Outcome results
None listed