Radiofrequency Ablation in Thyroid Nodules

Efficacy of Radiofrequency Ablation in Thyroid Nodules

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT01750593

Enrollment

Registered

2012-12-17

Start date

2013-04-30

Completion date

2014-06-30

Last updated

2013-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Nodules

Keywords

radiofrequency, thyroid, nodule

Brief summary

Thyroid nodules are common problems and although \> 95% are stated to be benign, they may cause some problems like hyperthyroidism, compression symptoms, and cosmesis associated with their function, size and localization. Especially for these nodules, patients undergo surgery and face up with the problems associated with surgical complications although they are not cancer. In some studies, radiofrequency ablation previously used for intrabdominal tumors like hepatic metastasis...,was stated to be efficient in the treatment of benign thyroid nodules and in some recurrent thyroid cancer cases. Therefore, the investigators decided to use this method in our patients having nodules like previously mentioned and see the efficacy and safety of the technique.

Interventions

PROCEDURERadiofrequency ablation of the thyroid nodule

Under USG control, the nodule will be ablated by radiofrequency with a needle that has an active tip of 1 cm.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

1. the presence of subjective symptoms (foreign body sensation, neck discomfort or pain, compressive symptom) or cosmetic problems; 2. a poor surgical candidate or refusal to undergo surgery; 3. fine-needle aspiration cytology and US findings that were compatible with a benign nodule; 4. anxiety about a malignancy.

Exclusion criteria

1. a nodule less than 5 mm in size; 2. follicular neoplasm or malignancy on fine needle aspiration cytology (FNAC); 3. a nodule with the sonographic criteria for a malignancy (taller than wide, marked hypoechoic, microcalcifications, ill-defined margins), although FNAC was a benign result; 4. previous radiation or operation history to the head and neck; (5) previous sclerosing therapy.

Design outcomes

Primary

Measure	Time frame
Shrinkage of the thyroid nodule after radiofrequency ablation	6 months

Secondary

Measure	Time frame
Disappearance of the nodules in follow up	1 year

Countries

Turkey (Türkiye)

Contacts

Primary ContactErhan Aysan, Prof. Dr.

erhanaysan@hotmail.com

Backup ContactYeliz Ersoy, Assoc.Prof

yelizemineersoy@yahoo.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026