Testicular Cancer
Conditions
Keywords
Physical activity, Testicular cancer, Chemotherapy, Feasibility
Brief summary
The purpose of this study is to determine the feasibility and effect of a program including information, counseling and an individualized physical activity program on physical and psychological health during and after chemotherapy in patients with testicular cancer. It is hypothesized that the patients are able to complete the intervention with individual adjustments.
Interventions
BEHAVIORALPhysical activity counseling
Sponsors
Norwegian School of Sport Sciences
Gjensidigestiftelsen
The Research Council of Norway
Oslo University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Seminoma/non-seminoma * Stage II-IV * 3-4 BEP(bleomycin,etoposide and cisplatin)or 4 EP(etoposide and cisplatin) * \> 18 years * Capable of reading and writing Norwegian
Exclusion criteria
* Conditions of a severity that contraindicate exercise without adjusted actions * Mentally incompetent conditions * Conditions of a severity that complicates the ability to participate in a supervised training program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Muscle strength, 1RM (one-repetition-maximum) | Baseline (0 weeks), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in 1RM from baseline to post-intervention and follow-up |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Body composition (Lean body mass and fat mass) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in body composition from baseline to post-intervention and follow-up |
| Metabolic disease markers (blood pressure, body mass index, glucose, high density lipoprotein cholesterol, triglycerides) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in metabolic disease markers from baseline to post-intervention and follow-up |
| C-reactive protein (CRP) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in CRP from baseline to post-intervention and follow-up |
| Creatinkinase (CK) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in CK from baseline to post-intervention and follow-up |
| Creatinkinase - MB (CK-MB) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in CK-MB from baseline to post-intervention and follow-up |
| Cardio respiratory fitness (VO2max) | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in VO2max from baseline to post-intervention and follow-up |
| Work status | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in work status from baseline to post-intervention and follow-up |
| Fatigue | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in fatigue from baseline to post-intervention and follow-up |
| Anxiety and depression | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in anxiety and depression from baseline to post-intervention and follow-up |
| Quality of life | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in quality of life from baseline to post-intervention and follow-up |
| Myoglobin | Baseline (0 week), post-intervention (9-12 weeks) and follow-up (24 weeks) | Change in myoglobin from baseline to post-intervention and follow-up |
Countries
Norway
Outcome results
None listed