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Increased Dietary Protein and Meal Frequency Reduces Total and Abdominal Body Fat During Weight Maintenance and Weight Loss

Increased Protein Intake and Meal Frequency Reduces Abdominal Fat and Increases Postprandial Thermogenesis During Energy Balance and Energy Deficit

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT01749449
Acronym
3v6
Enrollment
30
Registered
2012-12-13
Start date
2005-01-31
Completion date
2007-01-31
Last updated
2012-12-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Keywords

high protein, high carbohydrate, meal frequency, abdominal body fat, postprandial thermogenesis

Brief summary

The purpose of the current study was to examine the impact of macronutrient intake (PRO, 15% vs. 35%) and meal frequency (3 vs. 6 meals/day) on body composition, postprandial thermogenesis and plasma adipokines before and after 28days each of EB (28days) and ED (25%; 28days) in overweight individuals. We hypothesize that HP will elicit more favorable body composition, thermogenic, and cardiometabolic changes than HC intakes and the magnitude of change will be greatest in those consuming HP meals more frequently.

Interventions

OTHERprotein and meal frequency

comparison of different levels of protein intake and meal frequency on body composition in obese adults

Sponsors

Abbott
CollaboratorINDUSTRY
Skidmore College
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
30 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* 30-65 years old, * overweight or obese but otherwise in good health

Exclusion criteria

* cardiovascular disease, * cancer, * HTN, * type I or II DM, * food allergies

Design outcomes

Primary

MeasureTime frameDescription
body composition2 monthsDXA was used to quantify changes in body composition over the 2 months

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026