Muscle
Conditions
Keywords
soy, whey, casein, muscle, strength, protein
Brief summary
This study will investigate the effects of a soy/dairy protein blend on muscle growth and strength. In sports nutrition and in aging it is important to have healthy muscles. This can be achieved with exercise and nutrition. Consumption of protein following resistance exercise can promote healthy muscle growth and help improve strength. Young healthy men will be studied during a 12 week resistance exercise training program and be given protein supplements every day during the study. The hypothesis is that a blend of soy, whey and casein will induce a greater muscle gain and strength increase than the control.
Interventions
Sponsors
DuPont Nutrition and Health
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
MALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Stable body weight, healthy, males aged 18-35
Exclusion criteria
1. Exercise training (\>2 weekly sessions of moderate to high intensity aerobic or resistance exercise) 2. Resistance Training (\>2 weekly sessions of moderate to high intensity) within the past six months 3. Any orthopedic injury that prohibits participation in the exercise training 4. Significant heart, liver, kidney, blood, or respiratory disease 5. Peripheral vascular disease 6. Diabetes mellitus or other untreated endocrine disease 7. Active cancer (all groups) and history of cancer 8. Acute infectious disease or history of chronic infections (e.g. TB, hepatitis, HIV, herpes) 9. Recent (within 6 months) treatment with anabolic steroids, or corticosteroids. 10. Alcohol or drug abuse 11. Tobacco use (smoking or chewing) 12. BMI range will be (20-29.9 kg/m2) to exclude for Malnutrition (hypoalbuminemia, and/or hypotransferrinemia) and Obesity 13. Low hemoglobin levels (below normal values) 14. Food allergies (including milk and soy) 15. Individuals on a Vegetarian Diet 16. Females 17. Average protein intake \< 0.6 or \>1.8 g/kg per day 18. Taking dietary supplements such as green tea, creatine, ribose, whey or soy protein, etc. within the past 6 months 19. Currently on a high-soy diet or high dairy diet (consuming \>2 servings of soy per day or \>6 servings of dairy)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Muscle Mass | Baseline, 6 weeks, 12 weeks | Muscle Mass will be determined by DEXA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Muscle Strength | Baseline, 6 weeks, 12 weeks | Knee Extensor |
Countries
United States
Outcome results
None listed