HIV/AIDS
Conditions
Keywords
Veterans, HIV, AIDS, Cognitive Functioning, Suicide
Brief summary
The purpose of this project is to gather pilot data related to exploring relationships between cognitive impairment and/or psychiatric distress and suicidal thoughts and/or behaviors in Veterans with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS). To achieve this goal, a neuropsychological battery will be administered to Veterans with HIV/AIDS.
Interventions
None listed
Sponsors
VA Eastern Colorado Health Care System
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Veterans between ages 18 to 65 * Have a diagnosis of HIV/AIDS confirmed via medical record * Currently receiving or eligible to receive physical and/or mental health care through the VA Eastern Colorado Health Care System
Exclusion criteria
* Acute intoxication via alcohol or other illicit drugs at time of assessment as determined by observation and/or interview. * Psychosis at time of interview as determined by observation and/or interview. * Poor Test of Memory Malingering (TOMM) performance (scores below 25 on Trial 1 or scores lower than 45 on Trial 2) * Current status as a prisoner
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Delis-Kaplan Executive Function System (D-KEFS) | 1 Time Administration | Measure of executive functioning. |
| Brief VisuoSpatial Memory Test-Revised (BVMT-R) | 1 Time Administration | The BVMT-R measures immediate and delayed visual memory. |
| Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) | 1 Time Administration | The WAIS-IV is a widely used and well established instrument used to assesses an individual's intellectual functioning within various cognitive domains and organizes performance into several indices including Verbal Comprehension Index, Perceptual Reasoning Index, Working Memory Index, and Processing Speed Index. A composite, Full Scale IQ, is also generated to represent an estimation of overall intellectual functioning. |
| Trail Making Test (TMT): Parts A & B | 1 Time Administration | The TMT is a timed, pencil-paper, measure of attention, speed, and cognitive flexibility and requires participants to draw a line to accurately sequence 25 circles containing numbers (Part A) and alternating letters and numbers (Part B). |
| California Verbal Learning Test, Second Edition (CVLT-II) | 1 Time Adminstration | The CVLT-II examines several aspects of verbal learning, organization, and memory. |
| Wisconsin Card Sorting Test (WCST) | 1 Time Administration | Measure of executive functioning. |
| Outcome Questionnaire (OQ-45) | 1 Time Administration | The OQ-45 is a 45-item questionnaire that was designed to measure key areas of mental health functioning (symptom distress, interpersonal functioning, and social role). |
| Beck Scale for Suicide Ideation (BSS) | 1 Time Administration | The BSS is a 19-item scale that assesses severity of suicide ideation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Beck Hopelessness Scale (BHS) | 1 Time Administration | The BHS is a 20-item true-false self-report scale that measures the level of negative expectations about the future held by respondents. |
| The Beck Depression Inventory (BDI-II) | 1 Time Administration | The BDI-II is a widely used 21 item, self-administered instrument used to detect depression. |
| The Beck Anxiety Inventory (BAI) | 1 Time Administration | The BAI is a widely-used, 21-item, self-administered instrument used to measure the severity of an individual's anxiety. |
| Military Suicide Research Consortium (MSRC) Common Data Elements | 1 Time Administration | The Common Data Elements are a compilation of validated and reliable measures used to gather data on the risk factors for suicidal behavioral. |
| Health Status Questionnaire (HSQ) | 1 Time Administration | The HSQ is a 39-item, multiple choice, self-report measure that collects patient-reported, subjective data on eight subscales: Health Perception, Physical Functioning, Role Limitations/Physical Health, Role Limitations/Emotional Problems, Social Functioning, Mental Health, Bodily Pain and Energy/Fatigue. |
| University of Washington Risk Assessment Protocol-Revised (UWRAP) | 1 Time Administration | The UWRAP will be used to address potential risk associated with participating in the study. |
| Test of Memory Malingering (TOMM) | 1 Time Administration | The TOMM is a measure of effortful performance on objective tasks. |
| The Structured Clinical Interview for DSM-IV-Research Version (SCID-I) | 1 Time Administration | The SCID is a reliable and valid semi-structured interview used to make psychiatric diagnosis in both clinical and research settings. |
| Lifetime Suicide Attempt Self Injury Interview (L-SASI) | 1 Time Administration | The L-SASI was developed as a very brief survey of lifetime intentional self-harm behaviors and categorizes them into suicide attempts and non-suicidal acts. |
| Participant Demographics Form | 1 Time Administration | A questionnaire was created by members of the research team to collect data regarding demographics. |
| Ohio State University TBI-ID (OSU TBI-ID) Short Form | 1 Time Administration | The OSU TBI-ID Short Form will be used to determine history of TBI and presence of persistent TBI-related complaints. |
Countries
United States
Outcome results
None listed