Heart Failure
Conditions
Keywords
Heart Failure, Exercise and Physical Fitness
Brief summary
The investigators hypothesize that aerobic exercise training associated with respiratory muscle training will cause additional benefits compared to isolated exercise training or respiratory training in chronic heart failure patients.
Detailed description
The investigators hypothesize that aerobic exercise training associated with respiratory muscle training will cause additional benefits in the autonomic control and respiratory function compared to isolated exercise training or respiratory training in chronic heart failure patients.
Interventions
OTHERExercise training
The heart failure patients are subjected to differents protocols of physical training
Sponsors
Federal University of São Paulo
University of Sao Paulo General Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients with systolic heart failure and New York Heart Association (NYHA) class II-III * Left ventricular ejection fraction less than 40% * Peak Oxygen Consumption less than 20 ml/Kg/min
Exclusion criteria
* Chronic Obstructive Pulmonary Disease * Neuromuscular, Orthopedic, Neurologic and Neoplastic Diseases * Recent myocardial infarction or cardiac surgery (less than 6 months) * Unstable angina pectoris * Atrial Fibrillation * Pacemakers users * Actual Smoker * Pregnant * Changing medication or hospital admission
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Autonomic control | 4 months | Exercise training associated with inspiratory muscle training will reduce sympathetic nerve activity. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Functional Capacity | 4 months | Exercise training associated with inspiratory muscle training will improve peak oxygen consumption |
| Quality of life | 4 months | Exercise training associated with inspiratory muscle training will improve quality of life |
| Blood inflammatory markers | 4 months | Exercise training associated with inspiratory muscle training will reduces blood inflammatory markers |
| Muscular evaluation | 4 months | Exercise training associated with inspiratory muscle training will increase skeletal muscle strength |
| Respiratoy muscle function | 4 months | Exercise training associated with inspiratory muscle training will increase inspitarory muscle strength and endurance. |
Countries
Brazil
Outcome results
None listed