Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy

Effect of Enhanced Recovery After Surgery (ERAS) on Inflammatory Response After Planned Abdominal Hysterectomy: A Prospective Randomized Clinical Trial.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT01747005

Acronym

GERAS

Enrollment

Registered

2012-12-11

Start date

2012-06-30

Completion date

2015-12-31

Last updated

2015-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysterectomy

Keywords

abdominal hysterectomy, enhanced recovery after surgery, inflammatory response, ERAS, combined spinal-epidural anesthesia

Brief summary

The aim of study is to determine effect of enhanced recovery after surgery (ERAS) on inflammatory response after abdominal hysterectomy.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

* Informed consent * Abdominal hysterectomy * ASA class I or II

Exclusion criteria

* psychiatric disorders * ASA III and IV * Chronic inflammatory disorders * Pregnancy * Local anesthetics allergy * Coagulation disorders * patients receiving anticoagulants

Design outcomes

Primary

Measure	Time frame
Change of Serum level of IL-1beta,IL-6,CRP,Cortisol,IL-4 by immuno-ferment analysis.	baseline, 24 hour post-operative and 7 days post-operative

Secondary

Measure	Time frame	Description
Change of postoperative pain, fatigue and postoperative nausea and vomiting	baseline,6,12,24,48 hour and 7 days postoperatively	Postoperative pain will be assessed by visual analogue scale. Postoperative fatigue will be assessed by modified analogue scale. incidence of postoperative of nausea and vomiting

Countries

Russia

Contacts

Primary ContactEduard Ed. Antypin, MD

vard67@mail.ru0079600114083

Backup ContactAyyaz Hussain, MD

ayyaz@mail.ru0079115848504

Outcome results