Atypical Facial Pain or Atypical Odontalgia
Conditions
Keywords
atypical facial pain, atypical odontalgia, repetitive transcranial magnetic stimulation, neuropathic pain, chronic pain, assessment
Brief summary
Atypical Facial Pain is a chronic condition and presents controversies during diagnostic and treatment, between specialist not have consensus about the pathophysiology. It is possible consider this entitie a potential neuropathic cause without pathological signs. It knows the repetitive transcranial magnetic presents good results in the treatment of chronic pain coditions. The aim this study is evaluated the thresholds and excitability cortical in patients with AFP and verify the patterns of improvement in pain for patients undergoing rTMS compared to controls, as well as the therapeutic response to neuromodulation procedures. This enroll 20 patients with DAF and 20 controls treated with rTMS (5 sessions) and evaluated through questionnaires (EDOF clinical record, McGill Pain Questionnaire, Visual Analogue Scale, Inventory of symptoms of neuropathic pain, neuropathic pain DN4 questionnaire, SF -36, brief pain inventory). At the end of the data will be statistically analyzed and expressed as mean and standard deviation, and analyzed by Student's t test, analysis of variance (ANOVA), Tukey-Kramer and Pearson correlation. The level of significance is 5%. The results will be published in journals indexed in the area both nationally and internationally and presented at conferences and scientific meetings.
Interventions
PROCEDURErTMS
Patients undergoing of repetitive transcranial magnetic stimulation for treatment of AFP.
Sponsors
University of Sao Paulo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Fulfill criteria of Atypical Facial Pain by International Headache Society * Signed Term of Informed Consent
Exclusion criteria
* Trauma of Skull, epilepsy don't treated, * Use of medications decrease the seizure threshold * Patients in use of drugs, how cocaine and alcohol * neurosurgical clips, pacemakers, increased intracranial pressure (risk of sequelae after seizure) * Pregnant or lacting women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Baselin of Pain | base line (moment of inclusion) and end of each session rTMS (4X in three months) | Assessing by verbal analog scale (VAS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Excitability cortical | baseline (in the moment of inclusion) and end of each session of rTMS (4X in three months) | Changes in the measure of excitability cortical |
Countries
Brazil
Outcome results
None listed