Exercise, Fatigue
Conditions
Keywords
dietary supplement, carnosine
Brief summary
Beta-alanine, as a method to increase muscle carnosine, has been shown to enhance muscle buffering capacity and delay fatigue. Various fatigue tests have been utilized to examine the effectiveness of beta-alanine supplementation. The physical working capacity test has been used to show significant increases in physical working capacities following supplementation. The physical working capacity tests were originally developed by Moritani et al. 1981 and Devries et al. 1982 to measure the point of onset of muscular fatigue. It is hypothesized that beta-alanine will increase physical working capacity at heart rate threshold, thereby signifying a delay in fatigue.
Detailed description
An equal number of men and women will be recruited \[Men, n=20 (10 placebo \[PL\]; 10 beta-alanine (Active)\]; \[Women,n=20 (10 PL; 10 Active)\]. Men and women will be randomly assigned to respective groups to allow for equal numbers in supplement and placebo groups.
Interventions
DIETARY_SUPPLEMENTPlacebo
DIETARY_SUPPLEMENTBeta-alanine
Sponsors
University of North Carolina, Chapel Hill
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Between the ages of 18-35 years old * Be recreationally active (defined as accumulating 1-5 hours of moderate intensity
Exclusion criteria
* Any health risks or indicators that would prevent them from participating in physical activity, as determined by a health history questionnaire * Must not have taken performance enhancing supplements containing beta-alanine or creatine during the last 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical working capacity at heart rate threshold | 0 to 4 weeks |
Countries
United States
Outcome results
None listed