Respiratory Distress Syndrome, Adult
Conditions
Keywords
diaphragm movement, ultrasound, emergency room
Brief summary
The main objective of this study is to evaluate the inter-rater reproducibility of diaphragmatic excursion measures via time-motion-mode ultrasound (evaluation performed on the first measure) in patients experiencing acute respiratory distress emergencies.
Detailed description
The secondary objectives of this study are: * To assess the feasibility of measuring the diaphragmatic excursion in the context of emergency management (ratio of measured patients / included patients). * To evaluate the time required for the measurement. * To assess the intra-rater reproducibility of measurements of diaphragmatic excursion (comparison of first and second measures).
Interventions
PROCEDUREDiaphragm excursion measures 1
A first diaphragm ultrasound study will be carried out by investigator 1. A Vivid S6 GE Ultrasound will be used, with a phased array cardiac probe.
PROCEDUREDiaphragm excursion measures 2
A second diaphragm ultrasound study will be carried out immediately after Ultrasound 1, and by investigator 2. The results are blinded between investigators. A Vivid S6 GE Ultrasound will be used, with a phased array cardiac probe.
Sponsors
Centre Hospitalier Universitaire de Nīmes
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* The patient must have given his/her informed and signed consent * The patient must be insured or beneficiary of a health insurance plan * The patient has acute respiratory distress defined by a respiratory rate \> 25, and / or signs of struggle and hypoxia, oxygen saturation (SpO2) \<90% and / or pH \<7.35 and carbon dioxide partial pressure (pCO2) \> 6 kPa (45 mm Hg) * The patient breathes spontaneously (no respirator)
Exclusion criteria
* The patient is participating in another study * The patient is in an exclusion period determined by a previous study * The patient is under judicial protection, under tutorship or curatorship * The patient or his/her representative refuses to sign the consent * It is impossible to correctly inform the patient, or to correctly inform his/her representative * The patient is pregnant, parturient, or breastfeeding * The patient has a neurological or neuromuscular disease that modifies diaphragm function/movement; this does not include cases of decompensation (polyradiculoneuropathy, Lou Gehrig's disease, Myasthenia ...). * Patient admitted with respiratory support treatment in progress * Patient admitted with respiratory failure requiring immediate implementation of mechanical ventilation, thus preventing ultrasound measurements
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Diaphragmatic excursion, first measure by investigator 1 | Baseline (day 0) | in centimeters |
| Diaphragmatic excursion, first measure by investigator 2 | Baseline (day 0) | in centimeters |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Feasibility (yes/no) | Baseline (day 0) | We were able to perform the required measurements (yes/no) |
| Diaphragmatic excursion, second measure by investigator 2 | Baseline (day 0) | (centimeters) |
| Diaphragmatic excursion, second measure by investigator 1 | Baseline (day 0) | (centimeters) |
| Time necessary to measure diaphragm movement amplitude (minutes) | Baseline (day 0) | — |
Other
| Measure | Time frame |
|---|---|
| Age | Baseline (day 0) |
| Sexe | Baseline (day 0) |
Countries
France
Outcome results
None listed